1. A-50-year-old man has a history of frequent episodes of renal colic with highcalcium renal stones. The most useful agent in the treatment of recurrent calcium stones is
(a) Mannitol
(b) Furosemide
(c) Spironolactone
(d) Hydrochlorothiazide
(e) Acetazolamide
Ans: D
2. Which of the following drugs is correctly associated with its site of action and maximal diuretic efficacy?
(a) Thiazides–distal convoluted tubute–10% of filtered Na+
(b) Spironolactone–proximal convoluted tubule –40%
(c) Bumetanide–thick ascending limb–15%
(d) Metolazone–collecting tubule–2%
(e) All of the above
Ans: A
3. Substance secreted into the blood by a neuron is
(a) Neurohormone
(b) Neuromodulator
(c) Neuromediator
(d) Neurotransmitter
Ans: A
4. Which of the following is a leukotriene receptor blocker?
(a) Alprostadil
(b) Aspirin
(c) Ibuprofen
(d) LTC4
(e) Zafirlukast
Ans: E
5. A molecule that stimulates nitric oxide synthase, especially the eNOS isoform, is
(a) Acetylcholine
(b) Citruline
(c) Isoproterenol
(d) Nitroglycerin
(e) Nitroprusside
Ans: A
6. The primary endogenous substrate for nitric oxide synthase is
(a) Acetylcholine
(b) Angiotensinogen
(c) Arginine
(d) Citruline
(e) Heme
Ans: C
7. Which of the following is a recognized effect of nitric oxide?
(a) Arrhythmia
(b) Bronchoconstriction
(c) Constipation
(d) Inhibition of acute graft rejection
(e) Pulmonary vasodilation
Ans: E
8. cAMP is an example of
(a) Neurohormone
(b) Neuromodulator
(c) Neuromediator
(d) Neurotransmitter
Ans: B
9. One effect that theophylline, nitroglycerin, isoproterenol, and histamine have in common is
(a) Direct stimulation of cardiac contractile force
(b) Tachycardia
(c) Increased gastric acid secretion
(d) Postural hypotension
(e) Throbbing headache
Ans: B
10. Which one of the following chemicals does not satisfy the criteria for a neurotransmitter role in the CNS?
(a) Acetylcholine
(b) Dopamine
(c) Glycine
(d) Nitric Oxide
(e) Substance P
Ans: D
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(a) Mannitol
(b) Furosemide
(c) Spironolactone
(d) Hydrochlorothiazide
(e) Acetazolamide
Ans: D
2. Which of the following drugs is correctly associated with its site of action and maximal diuretic efficacy?
(a) Thiazides–distal convoluted tubute–10% of filtered Na+
(b) Spironolactone–proximal convoluted tubule –40%
(c) Bumetanide–thick ascending limb–15%
(d) Metolazone–collecting tubule–2%
(e) All of the above
Ans: A
3. Substance secreted into the blood by a neuron is
(a) Neurohormone
(b) Neuromodulator
(c) Neuromediator
(d) Neurotransmitter
Ans: A
4. Which of the following is a leukotriene receptor blocker?
(a) Alprostadil
(b) Aspirin
(c) Ibuprofen
(d) LTC4
(e) Zafirlukast
Ans: E
5. A molecule that stimulates nitric oxide synthase, especially the eNOS isoform, is
(a) Acetylcholine
(b) Citruline
(c) Isoproterenol
(d) Nitroglycerin
(e) Nitroprusside
Ans: A
6. The primary endogenous substrate for nitric oxide synthase is
(a) Acetylcholine
(b) Angiotensinogen
(c) Arginine
(d) Citruline
(e) Heme
Ans: C
7. Which of the following is a recognized effect of nitric oxide?
(a) Arrhythmia
(b) Bronchoconstriction
(c) Constipation
(d) Inhibition of acute graft rejection
(e) Pulmonary vasodilation
Ans: E
8. cAMP is an example of
(a) Neurohormone
(b) Neuromodulator
(c) Neuromediator
(d) Neurotransmitter
Ans: B
9. One effect that theophylline, nitroglycerin, isoproterenol, and histamine have in common is
(a) Direct stimulation of cardiac contractile force
(b) Tachycardia
(c) Increased gastric acid secretion
(d) Postural hypotension
(e) Throbbing headache
Ans: B
10. Which one of the following chemicals does not satisfy the criteria for a neurotransmitter role in the CNS?
(a) Acetylcholine
(b) Dopamine
(c) Glycine
(d) Nitric Oxide
(e) Substance P
Ans: D
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