16- A study of the intellectually handicapped was performed. The 112 subjects, put through program A, showed an increase in their mean IQ score of 6 points. The 115 subjects, put through program B, showed an increase in their mean IQ score of 4. The p value was >0.05 . Which of the following is true:
1) the numbers are too large for a Student t-test
2) the study demonstrates the usefulness of program A
3) the distribution of individual values is not important
4) even though the difference between the means is not significant it would be appropriate to calculate confidence intervals
5) the above results would be found by chance in less than 1:20
Answers-4
17- A study of an established antihypertensive agent against placebo reports that the risk of death due to cardiac causes is lower on treatment. It gives 5-year mortality due to cardiac causes as 12% on placebo and 8% on treatment. The authors conclude that 'a 33% reduction in cardiac deaths is seen with treatment'.
The figure '33%' represents which of the following?
1) Absolute Risk Reduction
2) Control Event Rate
3) Experimental Event Rate
4) Number Needed to Treat
5) Relative Risk Reduction
Answers-5
18 -A new antiplatelet agent has been proven to reduce the risk of stroke in a year from 10% in patients treated with conventional treatment to 6% in patients treated with conventional treatment plus the new agent. The cost of this new drug is £100 per month.
How much would a hospital need to spend to prevent one stroke.
42
1) £1200
2) £6000
3) £18000
4) £30000
5) £100000
Answers-4
19- A randomised, double-blind, placebo controlled trial of a cholesterol lowering drug in the primary prevention of coronary heart disease is reported.
1000 subjects are treated with the active drug, and 1000 are given placebo. They are followed up over a five year period and 100 individuals in the placebo group and 80 in the treatment group suffer a myocardial infarction.
What is the annual percentage risk of myocardial infarction in the group treated with placebo?
1) 0.5%
2) 2%
3) 5%
4) 8%
5) 10%
Answers-2
20 -A letter published in a medical journal suggests that an established antidepressant may cause photosensitivity. The manufacturer wishes to set up a study to determine rapidly and efficiently whether this is a true association.
Which one of the following techniques is most appropriate?
1) case control study
2) dose ranging study
3) double blind, randomized, placebo controlled study
4) meta-analysis
5) sequential trial
Answers-1
1) the numbers are too large for a Student t-test
2) the study demonstrates the usefulness of program A
3) the distribution of individual values is not important
4) even though the difference between the means is not significant it would be appropriate to calculate confidence intervals
5) the above results would be found by chance in less than 1:20
Answers-4
17- A study of an established antihypertensive agent against placebo reports that the risk of death due to cardiac causes is lower on treatment. It gives 5-year mortality due to cardiac causes as 12% on placebo and 8% on treatment. The authors conclude that 'a 33% reduction in cardiac deaths is seen with treatment'.
The figure '33%' represents which of the following?
1) Absolute Risk Reduction
2) Control Event Rate
3) Experimental Event Rate
4) Number Needed to Treat
5) Relative Risk Reduction
Answers-5
18 -A new antiplatelet agent has been proven to reduce the risk of stroke in a year from 10% in patients treated with conventional treatment to 6% in patients treated with conventional treatment plus the new agent. The cost of this new drug is £100 per month.
How much would a hospital need to spend to prevent one stroke.
42
1) £1200
2) £6000
3) £18000
4) £30000
5) £100000
Answers-4
19- A randomised, double-blind, placebo controlled trial of a cholesterol lowering drug in the primary prevention of coronary heart disease is reported.
1000 subjects are treated with the active drug, and 1000 are given placebo. They are followed up over a five year period and 100 individuals in the placebo group and 80 in the treatment group suffer a myocardial infarction.
What is the annual percentage risk of myocardial infarction in the group treated with placebo?
1) 0.5%
2) 2%
3) 5%
4) 8%
5) 10%
Answers-2
20 -A letter published in a medical journal suggests that an established antidepressant may cause photosensitivity. The manufacturer wishes to set up a study to determine rapidly and efficiently whether this is a true association.
Which one of the following techniques is most appropriate?
1) case control study
2) dose ranging study
3) double blind, randomized, placebo controlled study
4) meta-analysis
5) sequential trial
Answers-1
No comments:
Post a Comment