21- Statistical independence may be assumed in which of the following circumstances?
1) Successive measures taken on the same individual.
2) Stratified sampling from a target population.
3) Two matched individuals in a case control study.
4) Response to antibiotics of children with otitis media who have a CRP of above
5) Diagnosis of pyloric stenosis by ultrasound scan in patients attending a tertiary referral centre.
Answers-2
22- A study has been designed to investigate whether a certain drug plus physiotherapy treatment is better than drug treatment alone in the management of rheumatoid arthritis. After randomizing the patients a small proportion of the drug plus physiotherapy group decide to drop out of the study or omit some treatment sessions specified in the research protocol. What is the correct way of analysing the subsequent data?
1) Assume the patients have withdrawn their consent
2) Exclude these patients from all analysis
3) Extend the trial recruitment to make up the numbers
4) Include these patient outcomes in the drug plus physiotherapy group
5) Interview the patients and report their group separately
Answers-4
23- In a chronic disease which has no known effective treatment, a new treatment is known to be effective in animal models and shows promise in short-term studies in patients.
There are some theoretical concerns about toxicity involving liver and bone marrow although no cases have been observed in studies so far.
What is the most appropriate next step in the drug's development?
1) case control study
2) No further studies should be done and drug development should be stopped
3) open study
4) randomised double blind placebo controlled study
5) randomised single blind placebo controlled study
Answers-3
24-In a study to find out if concentration of drug X is related to weight, subjects were given 500 mg of the drug and serum levels were measured two hours later. Which of the following is the best statistical test to evaluate the results?
1) Student's paired t-test
2) Chi squared test
3) Student's unpaired t-test
4) Log regression analysis
5) Pearsons coefficient
Answer-4
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1) Successive measures taken on the same individual.
2) Stratified sampling from a target population.
3) Two matched individuals in a case control study.
4) Response to antibiotics of children with otitis media who have a CRP of above
5) Diagnosis of pyloric stenosis by ultrasound scan in patients attending a tertiary referral centre.
Answers-2
22- A study has been designed to investigate whether a certain drug plus physiotherapy treatment is better than drug treatment alone in the management of rheumatoid arthritis. After randomizing the patients a small proportion of the drug plus physiotherapy group decide to drop out of the study or omit some treatment sessions specified in the research protocol. What is the correct way of analysing the subsequent data?
1) Assume the patients have withdrawn their consent
2) Exclude these patients from all analysis
3) Extend the trial recruitment to make up the numbers
4) Include these patient outcomes in the drug plus physiotherapy group
5) Interview the patients and report their group separately
Answers-4
23- In a chronic disease which has no known effective treatment, a new treatment is known to be effective in animal models and shows promise in short-term studies in patients.
There are some theoretical concerns about toxicity involving liver and bone marrow although no cases have been observed in studies so far.
What is the most appropriate next step in the drug's development?
1) case control study
2) No further studies should be done and drug development should be stopped
3) open study
4) randomised double blind placebo controlled study
5) randomised single blind placebo controlled study
Answers-3
24-In a study to find out if concentration of drug X is related to weight, subjects were given 500 mg of the drug and serum levels were measured two hours later. Which of the following is the best statistical test to evaluate the results?
1) Student's paired t-test
2) Chi squared test
3) Student's unpaired t-test
4) Log regression analysis
5) Pearsons coefficient
Answer-4
More Questions & Answers:-
Page1 Page2 Page3 Page4 Page5
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