Monday, 2 November 2015

Most recent asked Infectious Diseases Objective Type Questions And Answers

61- Which of the following statement is true of infections with Mycobacterium tuberculosis:
1) non-sputum producing patients are non-infectious
2) a positive tuberculin test indicates active disease
3) lymph node positive disease requires longer treatment than pulmonary disease
4) in pregnant women treatment should not be given until after delivery
5) pyrazinamide has high activity against active extracellular organisms

62- Which of the following statements concerning zoonotic diseases is true?
1) Brucellosis is characterised by neutrophil leucocytosis.
2) Brucellosis is a recognised cause of spondylitis.
3) Toxoplasmosis causes visceral larva migrans.
4) Toxoplasmosis causes posterior uveitis.
5) Serological evidence of toxoplasmosis is rare in adults.

63- A 42-year-old man with advanced HIV disease presented with a tonic-clonic seizure. He had been diagnosed with HIV 10 years previously, but had elected not to take antiretroviral therapy. A CT scan of his brain showed a 2 cm ring-enhancing lesion in the right parietal lobe.
What is the probable causative agent?
1) Cryptococcus neoformans
2) Mycobacterium avium intracellulare
3) Mycobacterium tuberculosis
4) Pneumocystis carinii
5) Toxoplasma gondii

64- In herpes simplex encephalitis which of the following statements is correct?
1) brain MRI is characteristically normal
2) temporal lobe involvement is common
3) fits are uncommon
4) cold sores or genital herpes are usually present
5) viral identification by PCR on cerebrospinal fluid is non-specific

65- A 52-year-old woman was admitted with malaise and leg weakness.
Her illness started with a sore throat while travelling in Eastern Europe. On examination she was febrile (39.1°C) with several areas of exudates on her pharynx and extensive cervical lymphadenopathy. There was weakness of the legs with absent tendon reflexes.
What is the most likely diagnosis?
1) Acute myeloid leukaemia
2) Cytomegalovirus infection
3) Diphtheria
4) Glandular fever
5) Streptococcal tonsillitis

66- Which of the following concerning Corynebacterium diphtheriae is correct?
1) Causes skin infection
2) Infection is often complicated by myocardial fibrosis after recovery from severe infection
3) Is most unlikely to cause infection in an individual with a positive Schick test
4) Mitis strain is generally more virulent than the intermedius strain
5) Toxin is better absorbed through the nasal than the pharyngeal mucosa

67- A 43-year-old woman develops a progressive, ascending motor weakness over several days. She is hospitalized and requires intubation with mechanical ventilation. She is afebrile. A lumbar puncture is performed with normal opening pressure and yields clear, colorless CSF with normal glucose, increased protein, and cell count of 5/microliter, all lymphocytes. She gradually recovers over the next month. Which of the following conditions most likely preceded the onset of her illness?
1) Ketoacidosis
2) Staphylococcus aureus septicemia
3) Systemic lupus erythematosus
4) Viral pneumonia
5) Vitamin B12 deficiency

68- Which of the following is true of anthrax?
1) It is caused by an aerobic, gram negative rod.
2) It causes trivial disease in the host herbivore population.
3) Gastrointestinal anthrax is the most usual form of disease in humans.
4) Eshars are usually painless.
5) Sputum culture has a high yield in inhalational anthrax.

69- Which of the following forms of encephalitis is caused by a neuroimmunological response?
1) Herpes simplex
2) Measles
3) HIV infection
4) Enteral viruses
5) Cytomegalovirus

70- A 40-year-old man with a long history of alcohol abuse is admitted with a subacute illness, comprising headache, fever, meningism and ataxia. MRI brain showed patchy high signal abnormality of the brain stem. CSF analysis showed polymphonuclear pleocytosis and low glucose. He had failed to improve after 3 days of intravenous cefotaxime treatment. The most likely diagnosis of the meningitis is:
1) Mycobacterium tuberculosis
2) Cryptococcus neoformans
3) Nocardia asteroides
4) Staphyloccus aureus
5) Listeria monocytogenes

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