Friday, 8 January 2016

Freshers Bio-technology Interview Questions and Answers pdf

21. Name some common allergens associated with type-I hypersensitivity.
Penicillin, sulfonamide, eggs, milk, dust mites, animal air, vaccines etc.

22. What is atopy?
The tendency to manifest localized anaphylactic reactions is called atopy.

23. Who are atopic individuals?
Atopic individuals are those who are having abnormal high levels of circulating IgE and more than normal number of oesinophils.

24. Where do most allergic reactions occur?
Most of them occur on mucous membrane. Allergens enter the body by the process of inhalation or ingestion.

25. What is P-K reaction?
The response produced when an allergen is injected into an individual, who is sensitive is called P-K reaction.

26. What are high affinity receptors?
Mast cells and basophils express high affinity receptor. The high affinity enables it to bind with IgE, despite low serum concentration of IgE.

27. What are low affinity receptors?
Low affinity receptors play role in regulating he intensity of IgE response.

28. What are primary mediators?
Primary mediators are those, which are produced before degranulation. These primary mediators are stored in granules. Some of the primary mediators are histamine, heparin, proteases etc.

29. What are secondary mediators?
Secondary mediators are produced after target cell activation or released by the break down of phospholipids membrane during the process of degarnulation. Some of the secondary mediators are leukotrienes, various cytokines, prostaglandins etc.

30. Explain in brief about histamine
It is formed by the decarboxylation of amino acid histidine. It accounts for 10% of granule weight. This histamine binds to specific receptors on various target cells.

More Questions & Answers:-
Page1 Page2 Page3 Page4 Page5 Page6 Page7 Page8 Page9 
Page10 Page11

No comments:

Post a Comment