Wednesday 28 October 2015

Analagesics & Antipyretics Objective Type Questions And Answers

11. Which one of the following statements about dextromethorphan is accurate?
(a) Activates kappa receptors
(b) Analgesia equivalent to pentazocine
(c) Highly effective antiemetic
(d) Less constipation than codeine
(e) Use requires a prescription
Ans: D

12. Which one of the following effects does not occur in salicylate intoxication ?
(a) Hyperventilation
(b) Hypothemia
(c) Metabolic acidosis
(d) Respiratory alkalosis
(e) Tinnitus
Ans: B

13. Which one of the following drugs is not useful in dysmenorrhea?
(a) Aspirin
(b) Colchicine
(c) Ibuprofen
(d) Rofecoxib
(e) Naproxen
Ans: B

14. Following gold compound is generally administered orally
(a) Aurothioglucose
(b) Auronafin
(c) Gold sodium thiomalate
(d) All of the above
Ans: B

15. The main advantage of ketorolac over aspirin is that ketorolac
(a) Can be combined more safely with an opioid such as codeine
(b) Can be obtained as an over-the-counter agent
(c) Does not prolong the bleeding time
(d) Is available in a parenteral formulation that can be injected intramuscularly or intravenously
(e) Is less likely to cause acute renal failure in patients with some preexisting degree of renal impairment
Ans: D

16. A 45-year-old surgeon has developed symmetric early morning stiffness in her hands. She wishes to take a nonsteroidal anti-inflammatory drug to relieve these
symptoms and wants to avoid gastrointestinal side effects. Which one of the following drugs is most appropriate?
(a) Aspirin
(b) Celecoxib
(c) Ibuprofen
(d) Indomethacin
(e) Piroxicam
Ans: B

17. Following is an example of preformed and not lipid derived mast cell mediator of inflammatory process
(a) LTC4
(b) PGD2
(c) PAF
(d) Histamine
Ans: D

18. The toxicity spectrum of aspirin does not include
(a) Increased risk of encephalopathy in children with viral infections
(b) Increased risk of peptic ulcers
(c) Hyperprothrombinemia
(d) Metabolic acidosis
(e) Respiratory alkalosis
Ans: C

19. Accidental poisonings are common with both aspirin and ibuprofen, two OC drugs available in tasty chewable tablets. In cases of overdose, aspirin is more likely
than ibuprofen to cause
(a) Autonomic Instability
(b) Hepatic necrosis
(c) Metabolic acidosis
(d) Thrombocytopenia
(e) Ventricular arrhythmias
Ans: C

20. A drug that decreases blood pressure and has analgesic and spasmolytic effects when given intrathecally is
(a) Atenolol
(b) Clonidine
(c) Morphine
(d) Nitroprusside
(e) Prazosin
Ans: B

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