81. A patient suffers from spisodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from
(a) Angina pectoris
(b) Biliary colic
(c) Esophageal spasm
(d) All of the above
Ans: D
82. The dihydropyridines block the following type of calcium channels.
(a) L-type voltage sensitive channels
(b) T-type voltage sensitive channels
(c) N-type voltage sensitive channels
(d) Receptor operated calcium channels
Ans: A
83. Which of the following drugs is most likely to accentuate varient (Prinzmetal) angina ?
(a) Digoxin
(b) Furosemide
(c) Enalapril
(d) Amrinone
Ans: A
84. In cardiac cells, adenosine
(a) Causes shortening of action potential duration
(b) Depolarization
(c) Increase in normal automaticity
(d) All of the above
Ans: A
85. Which of the following antianginal drugs is most likely to produce tachycardia as a side effect ?
(a) Amlodipine
(b) Nifedipine
(c) Diltiazem
(d) Verapamil
Ans: B
86. Which of the following is not an attribute of amlodipine ?
(a) High and consistent oral bioavailability
(b) Large volume of distribution
(c) Generation of an active metabolite
(d) Long elimination half-life
Ans: C
87. Propranolol should not be prescribed for a patient of angina pectoris who is already receiving
(a) Nifedipine
(b) Felodipine
(c) Verapamil
(d) Isosorbide mononitrate
Ans: C
88. Which of the following drugs is a potassium channel opener ?
(a) Pinacidil
(b) Hydralazine
(c) Glibenclamide
(d) Amiloride
Ans: A
89. Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because
(a) They antagonize each other’s side effects
(b) Nitrates primarily reduce preload while calcium channel blockers primarily reduce after load
(c) Nitrates increase coronary flow while calcium
(d) Both (b) and (c)
Ans: B
90. ‘Coronary steal phenomenon’ has been noted most frequently with
(a) Glyceryl trinitrate
(b) Dipyridamole
(c) Propranolol
(d) Diltiazem
Ans: B
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(a) Angina pectoris
(b) Biliary colic
(c) Esophageal spasm
(d) All of the above
Ans: D
82. The dihydropyridines block the following type of calcium channels.
(a) L-type voltage sensitive channels
(b) T-type voltage sensitive channels
(c) N-type voltage sensitive channels
(d) Receptor operated calcium channels
Ans: A
83. Which of the following drugs is most likely to accentuate varient (Prinzmetal) angina ?
(a) Digoxin
(b) Furosemide
(c) Enalapril
(d) Amrinone
Ans: A
84. In cardiac cells, adenosine
(a) Causes shortening of action potential duration
(b) Depolarization
(c) Increase in normal automaticity
(d) All of the above
Ans: A
85. Which of the following antianginal drugs is most likely to produce tachycardia as a side effect ?
(a) Amlodipine
(b) Nifedipine
(c) Diltiazem
(d) Verapamil
Ans: B
86. Which of the following is not an attribute of amlodipine ?
(a) High and consistent oral bioavailability
(b) Large volume of distribution
(c) Generation of an active metabolite
(d) Long elimination half-life
Ans: C
87. Propranolol should not be prescribed for a patient of angina pectoris who is already receiving
(a) Nifedipine
(b) Felodipine
(c) Verapamil
(d) Isosorbide mononitrate
Ans: C
88. Which of the following drugs is a potassium channel opener ?
(a) Pinacidil
(b) Hydralazine
(c) Glibenclamide
(d) Amiloride
Ans: A
89. Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because
(a) They antagonize each other’s side effects
(b) Nitrates primarily reduce preload while calcium channel blockers primarily reduce after load
(c) Nitrates increase coronary flow while calcium
(d) Both (b) and (c)
Ans: B
90. ‘Coronary steal phenomenon’ has been noted most frequently with
(a) Glyceryl trinitrate
(b) Dipyridamole
(c) Propranolol
(d) Diltiazem
Ans: B
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